Liver



Human Transporter
Gene
PCT
ITC/FDA
EMA
Japan
OATP1B1
SLCO1B1
yes
+
+
+
OATP1B3
SLCO1B3
yes
+
+
+
OATP2B1
SLCO2B1
yes
OATP2A1
SLCO2A1
yes
OCT1
SLC22A1
yes
consider
+
OCTN2
SLC22A5
yes
+
OAT2
SLC22A7
yes
OAT7
SLC22A9
upon request
MATE1
SLC47A1
yes
+
consider
+
MDR1 (P-gp)
ABCB1
yes
+
+
+
BCRP
ABCG2
yes
+
+
+
BSEP
ABCB11
yes
consider
consider
NTCP
SLC10A1
yes
NaDC3
SLC13A3
yes
MRP3
ABCC3
upon request
MRP4
ABCC4
upon request
MRP6
ABCC6
upon request
MDR3
ABCB4
upon request
ENT1
SLC29A1
upon request
ENT2
SLC29A2
upon request
OST a
SLC51A
upon request
OST b
SLC51A
upon request


Upon request we are able to stably overexpress each membrane transporter protein into HEK293 cell line.

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